Copy of Rheumatology Module 3

In the management of RA in pregnancy, which of the following drug is contraindicated?

The following genes are associated with risk of developing RA except?

The following cells are predominantly found in RA synovial tissue except?

Which of the following cytokines is NOT of key importance in RA pathogenesis?

Bone erosion in RA is mediated by which cell?

The following are required to support osteoclast development in RA, except?

Which of the following are not readily detectable in the joints of patients with RA?

In which of the following condition is the DIP joint spared?

Which one of the following condition causes high titers of rheumatoid factor?

What is the most common cause for false positive rheumatoid factor?

Which of the following marker is highly predictive of RA in asymptomatic and early undifferentiated arthritis?

An asymptomatic patient is found to have anti-CCP positivity.

What is the biggest risk factor for the development of RA in the future?

The following are predictors of severity of RA except?

Which of the following indicate activity of RA?

Which of the following are risk factors for RA development?

A patient with RA on methotrexate develops severe pneumonitis and bone marrow suppression.

The most appropriate additional treatment at this stage is?

Which of the following is a chimeric Ab to TNF?

A patient with RA is found to have latent TB .What should be done prior to treatment with a TNF blocker?

A 68 year old man with severe RA treated with adalimumab, methotrexate and prednisone presents with 3 days history of fever and rigors.

What is the most likely organism?

What is the mechanism of action of Rituximab?

All of the following are targets of DMARDs except?

Which of the following group of patients should not be considered for biological DMARDs?

A 47-year-old man with a history of chronic sinusitis presents with shortness of breath to the Emergency Department. Initial investigations reveal: Hb 10.4g/dl Platelets 477 * 109/l WCC 14.3 * 109/l ESR 92 mm/h Urea 20 mmol/l Creatinine 198 mmol/l Urine dipstick blood +++

What is the most likely diagnosis?

Which of the following features are not typically seen in a patient with adult onset Still’s disease?

Which one of the following statements concerning discoid lupus is correct?

Which one of the following is the most common ocular manifestation of rheumatoid arthritis?

Which one of the following is least recognised as a risk factor for developing osteoporosis?

Each one of the following is seen in reactive arthritis, except:

Which imaging modality would be useful as a guide for muscle biopsy in dermatomyositis?

Which of the following is the most useful test for assessment of disease activity in systemic lupus erythematosus?