Infectious Diseases Module 5

A 45-year-old male with a history of type 2 diabetes mellitus presents to the emergency department with a red, swollen, and painful leg. He has had a fever for the past 24 hours, and the skin over his left lower leg is erythematous and warm to the touch, with visible streaking.

On examination, there is significant swelling and tenderness over the affected area. The diagnosis of cellulitis is made, and empirical treatment with intravenous flucloxacillin is initiated.

The following day, his left leg still appears very erythematous, so the medical team decided to add probenecid to the treatment regimen.

What is the benefit of adding probenecid in this situation?

A 65-year-old female patient with a history of diabetes mellitus and recurrent urinary tract infections presents for a routine follow-up visit.

She denies any urinary symptoms at this time. Urinalysis shows significant bacteriuria (>100,000 CFU/mL of a single uropathogen) without pyuria.

What is the most appropriate management of this patient?

What is the most common organism that causes cellulitis?

A 28-year-old sexually active male presents with painless genital ulcers that resolved on their own. He now complains of new-onset inguinal lymphadenopathy that is tender and fluctuant.

On further examination, the patient has serous or serosanguinous discharge from the urethra.

What is the most likely diagnosis in this case?

What is the most common adverse pregnancy outcome in untreated syphilis?

Which of the following is the most common genotype found in Extended-Spectrum Beta-Lactamase (ESBL) producing bacteria?

A 32-year-old male patient diagnosed with syphilis is being monitored for treatment response using RPR (Rapid Plasma Reagin) titres.

What is the correct interpretation of the RPR/VDRL titres in determining cure from syphilis?

Which of the following is the most common sexually transmitted infection (STI) across New Zealand and Australasia?

Which route causes the highest transmission rate of gonorrhea?