Infectious Diseases Module 2

A patient suspected to have bacterial meningitis has been commenced on IV ceftriaxone and benzyl penicillin together with dexamethasone.Cultures have revealed Listeria monocytogenes.

What should be the next step?

A patient with known HIV has the following CSF findings:

• JC virus positive.
• Toxoplasma negative
• EBV negative
• CMV negative
• TB negative
• Cryptococcus negative
• serum anti-toxoplasma IgG negative
• CT scan: Multiple hypodense non enhancing cerebral white matter lesions involving the cerebellum and brain stem.no mass effect.

What is the most likely diagnosis?

A patient suspected to have bacterial meningitis has been commenced on IV ceftriaxone and benzyl penicillin together with dexamethasone.Cultures have revealed Strep pneumoniae with an MIC of 1.5 mg/L for ceftriaxone.

Which should be the antibiotic of choice?

CMV prophylaxis is recommended in the following patient group except?

What is the most common cause of aseptic meningitis?

Which of the following procedure is NOT an indication for antibiotic prophylaxis?

What is the recommended empiric antibiotic regime for brain abscess following a penetrating trauma where the source of organism is still unknown?

Which of the following antibiotic does NOT have a role in the treatment of brain abscess?

A patient is suspected to have necrotising fasciitis secondary to a Group A Streptococcal infection.

Besides, early surgical debribement, what would be the antibiotic of choice?

A patient who has an indwelling vascular catheter for TPN develops fever and a new murmur and therefore suspected to have infective endocarditis.

What is the most likely culprit organism?

The following are causes for culture negative endocarditis except?

The following are major criterion for the diagnosis of infective endocarditis based on the modified Duke’s criteria, except?

A patient with early syphilis is treated with intramuscular procaine penicillin (long acting) 1g daily for 10 days.

What is the rationale for the use of this antibiotic?

Which of the following test is best used to monitor disease activity in syphilis?

Which of the following antibiotic has no role in the treatment of Mycobacterium avium complex (MAC) infection?

What is the most commonly reported adverse reaction of the seasonal influenza vaccine in New Zealand?

Which of the following factor is a major risk determinant for perinatal transmission of hepatitis C virus?

The annual influenzae epidemics best explained by which of the following mechanisms?

The effect of neuraminidase inhibitors (such as zanamivir) when given within 24 hours of onset of symptoms on the course of influenza infection is best described as:

Which of the following best describes the antiviral effect of Oseltamivir on the influenza virus?

What is the most sensitive and specific test for the diagnosis of pertussis?

Which one of the following vaccines would be the most inappropriate for an immunosuppressed patient?

A 57 year old patient is suspected to have bacterial meningitis. A lumbar puncture is performed and the CSF reported a growth of gram positive bacilli on gram stain.

What is the most likely organism?

Which one of the following is the most likely cause of vancomycin resistance in enterococci?

Which of the following best describes the mechanism of resistance of Haemophilus influenzae to ampicillin?

Which of the following best describes the mode of action of aminoglycoside antibiotics?

Which of the following is most predictive of the presence of multi-drug resistance in a patient with tuberculosis infection?

In adults older than 65, which vaccine is most likely to improve survival?