Copy of Endocrinology Module 5

Which of the following will most likely improve the chance of longevity in life?

What is the best intervention to prevent thyroid eye disease?

What is the best treatment of solitary toxic nodules?

Jod basedow effect is a phenomenon where there is iodine induced hyperthyroidism. Which of the following is associated with this effect?

What is the mechanism of Type II Amiodarone induced thyrotoxicosis?

The following feature suggests a Type II rather than a Type I Amiodarone induced thyrotoxicosis

The following feature suggest a benign thyroid nodule rather than malignant:

Which of the following is NOT an ultrasonographic feature of thyroid malignancy?

A 37 year old patient has a thyroid nodule more than 4cm with benign cytology.

What is the most appropriate next step in management?

Of all palpable thyroid nodules, what percentage are actually malignant?

A 42 year old male was found to have a primary thyroid tumour measuring more than 1 cm.

What is the next appropriate step in management?

A patient recently diagnosed with primary thyroid tumor has undergone a total thyroidectomy .

What is the next step in management?

Which of the following decreases in thyrotoxicosis?

TSH is the best marker of thyroid status for the following conditions except?

Which of the following condition has the highest rate of positivity to anti-thyroid peroxidase antibody?

What is the half life of T4?

Which of the following is not beneficial in the treatment of amiodarone induced thyroiditis?

Thyroid ultrasound is most helpful in the following condition:

Which of the following intervention would be most effective in preventing recurrence of non-metastatic papillary thyroid cancer following a total thyroidectomy?

What is the most common type of thyroid cancer?

Which of the following carries the highest mortality?

What is the rationale for giving high dose radioactive iodine following thyroidectomy for papillary thyroid carcinoma?

A 42 year old patient presents with an enlarging neck mass. The serum TSH is normal. Neck ultrasound shows a 2cm homogenous mass consistent with thyroid nodule.

What is the most appropriate next step in management?

A 26 year old Chinese male presented with an episode of collapse after performing some strenuous exercise. On examination, he has flaccid paralysis of both legs, reduced power in the arms and a weak voice. Reflexes are absent in the arms and legs but sensation is intact. He also has bilateral ptosis and prominent symmetrical goiter. His heart rate is 140 with fine tremors on fingers.

Which test is most helpful to explain his recent collapse?

In patients with subclinical hyperthyroidism, what is the strongest indication for recommending radioiodine treatment?

The following hormone is capable of activating the TSH receptor on the thyroid gland:

A patient was diagnosed with papillary carcinoma in the left lobe of thyroid and underwent a subtotal thyroidectomy 4 years ago.

She was advised that surgery had cured her cancer and was not offered any further treatment or follow up.

She is on no medication. She is clinically euthyroid and no mass is palpable on examination. Ultrasound shows no evidence of lymphadenopathy or thyroid mass.

What is the next step in management?

Which of the following scenarios would best explain the following TFT results?

• TSH 3.2 (0.4-4.0)
• fT4 37 (9-19)
• fT3 8.2 (3.5-6.5)

A 48 year old man is reviewed 6 months following a trans-sphenoidal resection of a non functioning macroadenoma.He has been commenced on thyroxine 3 months following his surgery.

Now he complains of increasing fatigue and weight gain.

TFT, Testosterone and Cortisol all normal.

What is the most likely diagnosis?