Immunology Module 4

A 15 year old male presents with acute onset of upper airway obstruction.Has a positive family history of hereditary angioneurotic edema.

Which of the following is the most appropriate treatment?

A 15 year old male presents with recurrent attacks of angioedema.Had a previous abdominal surgery when he presented with an acute abdominal pain a year ago but there was no surgical cause found.

Lab findings:

C4 reduced

C3 normal

C1-Inhibitor reduced

C1q levels are low

What is the most likely diagnosis?

Which one of the following biologically active components of the complement cascade is most directly responsible for the formation of transmembrane channels leading to cell lysis?

Which of the following immunoglobulins fix complement when they bind to antigen?

Which one of the following major immunoglobulin classes in the human fixes the alternate complement pathway?

The protein shared by the alternate and classical complement systems is:

A defect of which component of immune function is most likely to be associated with gingivitis?

A 26-year-old newly qualified nurse presents as she has developed a bilateral erythematous rash on both hands. She has recently emigrated from the Philippines and has no past medical history of note. A diagnosis of contact dermatitis is suspected.

What is the most suitable to test to identify the underlying cause?

Which primary disorder is characterized by absence of B cells?

For antigen recognition, the T cell requires the antigen to be processed and expressed with HLA.

Which HLA class does the T cell require for CD4 cells?

Which one of the following is NOT an antigen presenting cell?

How does the Herpes Simplex virus escapes from being recognized by the APC?

The following are effects of Dendritic cell activation except?

All of the following cells express HLA class I except?

The following statements are TRUE regarding dendritic cells except?

The rise in serum beta 2 microglobulin holds a significant prognostic factor in which condition?

Which one of the following is associated with a Type 1 allergy?

Serum tryptase is only helpful if collected within hour many hours following an IgE mediated reaction?

The following drugs are commonly known to cause an anaphylactoid reaction except?

The following are chemical mediators released by mast cells in anaphylaxis except?

Which one of the following test is the most specific for the diagnosis of NSAIDs hypersensitivity?

Skin prick testing is useful for the following conditions except for the testing of an allergy to?

The following are risk factors for radioiodine contrast allergy except?

A 5 year old boy collapses with wheeze and hypotension during an imaging procedure. He responds quickly to resuscitation.

On review two hours later, which test would be most helpful for confirming a reaction to contrast media?

Which of the following cytokines is most likely to result in hepatic formation of inflammatory markers such as the CRP?

Which of the following acute phase proteins decreases with inflammation?

Which of the following cytokine is not responsible for the hepatic formation of inflammatory markers such as the CRP?

A patient with Sjogren’s syndrome presents with acute pancreatitis. This condition is most likely to respond to steroids if:

Which of the following statement is correct regarding CTLA-4?

A 15-year-old male presents with acute onset of symptoms of upper airway obstruction.

He has a history of hereditary angioneurotic oedema.

Which of the following is the most effective therapy?

Expression of which of the following cell surface molecules best defines a stem cell?

Which of the following HLA chains shows least allelic polymorphism?

A 14 year old boy presents with recurrent facial and lip swelling.These episodes are associated with abdominal pain, diarrhea and vomiting.No urticaria.

Which of the following is the most appropriate investigation to establish the diagnosis?